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Mahesh Patel Selected Research

zidebactam

1/2020Effective inhibition of PBPs by cefepime and zidebactam in the presence of VIM-1 drives potent bactericidal activity against MBL-expressing Pseudomonas aeruginosa.
1/2019In Vitro and In Vivo Activities of β-Lactams in Combination with the Novel β-Lactam Enhancers Zidebactam and WCK 5153 against Multidrug-Resistant Metallo-β-Lactamase-Producing Klebsiella pneumoniae.
1/2017WCK 5107 (Zidebactam) and WCK 5153 Are Novel Inhibitors of PBP2 Showing Potent "β-Lactam Enhancer" Activity against Pseudomonas aeruginosa, Including Multidrug-Resistant Metallo-β-Lactamase-Producing High-Risk Clones.

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Mahesh Patel Research Topics

Disease

11Infections
01/2022 - 07/2010
2Respiratory Tract Infections (Respiratory Tract Infection)
01/2022 - 01/2019
1Albuminuria
12/2023
1Human Influenza (Influenza)
01/2022
1Phototoxic Dermatitis (Phototoxicity)
01/2022
1Bradycardia
01/2022
1Syncope (Fainting)
01/2022
1Bronchogenic Cyst
03/2021
1Weight Gain
01/2021
1Hypertension (High Blood Pressure)
01/2021
1Non-alcoholic Fatty Liver Disease
03/2020
1Alcoholic Fatty Liver
03/2020
1Acute Lung Injury
01/2020
1Wilms Tumor (Wilm's Tumor)
01/2016
1Body Weight (Weight, Body)
01/2016
1Solitary Kidney
01/2016
1HIV Infections (HIV Infection)
07/2010
1Endocarditis
05/2008
1Acute Coronary Syndrome
07/2005
1Dehydration (Water Stress)
03/2005

Drug/Important Bio-Agent (IBA)

5levonadifloxacinIBA
01/2022 - 01/2019
3Anti-Bacterial Agents (Antibiotics)IBA
01/2022 - 03/2005
3LactamsIBA
10/2021 - 01/2017
3cefepime-zidebactamIBA
10/2021 - 01/2020
3zidebactamIBA
01/2020 - 01/2017
2Penicillins (Penicillin)FDA Link
01/2022 - 01/2019
2MacrolidesIBA
01/2022 - 01/2019
2LipidsIBA
01/2021 - 07/2005
2WCK 5153IBA
01/2019 - 01/2017
1Angiotensin Receptor AntagonistsIBA
12/2023
1SodiumIBA
12/2023
1Glucose (Dextrose)FDA LinkGeneric
12/2023
1Glucagon-Like Peptide-1 ReceptorIBA
12/2023
1Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
12/2023
1WCK 771IBA
01/2022
1Levofloxacin (Levaquin)FDA Link
01/2022
1WCK 1153IBA
01/2022
1WCK 1152IBA
01/2022
1Oxazolidinones (2 Oxazolidone)IBA
01/2022
1Linezolid (Zyvox)FDA Link
01/2022
1GlycopeptidesIBA
01/2022
1ProdrugsIBA
12/2021
1IntegrasesIBA
01/2021
1Integrase InhibitorsIBA
01/2021
1Glucagon (Glukagon)FDA Link
03/2020
1FluoroquinolonesIBA
01/2020
1Cefepime (Maxipime)FDA LinkGeneric
01/2020
1LipopolysaccharidesIBA
01/2020
1efavirenz (Sustiva)FDA Link
01/2016
1CreatinineIBA
01/2016
1Tenofovir (Viread)FDA Link
01/2016
1Emtricitabine (Emtriva)FDA Link
01/2016
1Immunoglobulin M (IgM)IBA
07/2010
1Immunoglobulin G (IgG)IBA
07/2010
1IceIBA
05/2008
1TroponinIBA
05/2008
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
07/2005
1Sch 725424IBA
03/2005
1Sch 725428IBA
03/2005

Therapy/Procedure

1Cardiopulmonary Resuscitation (CPR)
01/2022
1Decompression
03/2021
1Art Therapy
01/2021
1Therapeutics
01/2021
1Nephrectomy
01/2016
1Drug Therapy (Chemotherapy)
01/2016
1Highly Active Antiretroviral Therapy (HAART)
07/2010
1Intraperitoneal Injections
07/2010
1Transplantation
07/2010